QS-21

QS-21 is a highly effective vaccine adjuvant widely used in various human vaccines, such as the shingles vaccine Shingrix and the respiratory syncytial virus vaccine Arexvy. By enhancing the immune system's response, it significantly improves the protective efficacy of vaccines.

The Importance of QS-21

QS-21 is a triterpenoid saponin composed of two isomers (QS-21 β-D-Apiofuranose and QS-21 β-D-Xylopyranose).

It can simultaneously activate Th1 and Th2 immune responses, significantly enhancing the immunogenicity of vaccines.QS-21 has been used in various vaccine adjuvant systems, such as AS01 (GlaxoSmithKline's Shingrix vaccine) and Matrix-M (Novavax's COVID-19 vaccine). However, traditional extraction methods are limited by the scarcity of Quillaja saponaria resources and the complexity of the extraction process, leading to insufficient supply and high costs.

Desert King's Innovative Production Technology

Desert King employs plant cell culture technology to produce QS-21, which not only eliminates reliance on natural resources but also significantly improves production efficiency. By optimizing culture conditions, Desert King can produce QS-21 that is highly consistent with natural QS-21 in both structure and function, while ensuring batch-to-batch consistency and high purity (≥96%).

Compared to traditional methods, plant cell culture technology offers the following advantages:

Sustainability: Reduces dependence on Quillaja saponaria resources and protects the environment.
Efficiency: Short production cycles and stable yields meet large-scale demand.
High Quality: High product purity and low endotoxin levels meet pharmaceutical standards.